Pivikto 150mg Tablet

Prescription Required Cold Chain i

Salt Composition ALPELISIB

Marketer NOVARTIS

Prepaid Only. Non-Returnable.

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Introduction to Pivikto 150mg Tablet

Pivikto 150 mg Tablet contains alpelisib, an anticancer medicine classified as a PI3K (phosphatidylinositol-3-kinase) inhibitor. It is mainly prescribed in combination with other cancer treatments for metastatic breast cancer in postmenopausal women and in men whose disease has progressed during or after previous therapies. It is also used in certain patients with PIK3CA-related overgrowth spectrum (PROS), a rare genetic disorder characterized by abnormal tissue growth and overgrowth.

Pivikto should be taken strictly according to your doctor’s instructions. Follow the prescribed dosage schedule carefully, and store the tablets as directed to maintain their effectiveness. Patients with kidney or liver problems should inform their healthcare provider before starting treatment, as dose adjustments or close monitoring may be required. Regular monitoring is important during therapy, particularly for potential side effects such as high blood sugar (hyperglycemia).

Women who are pregnant, planning to become pregnant, or breastfeeding should consult their doctor before using this medication, as it may not be safe during pregnancy. Long-term treatment requires ongoing medical supervision and regular follow-up appointments to assess safety and effectiveness.

Pivikto is manufactured by Novartis India, and the price may vary depending on the pharmacy and location. It is available for purchase from authorized pharmacies, including online platforms, with a valid prescription. Patients should also discuss possible alternative options with their doctor if needed.

Uses of Pivikto 150mg Tablet

Pivikto 150 uses are

HER2- negative Breast cancer

Therapeutic Effects of Pivikto 150mg Tablet

This medication acts on specific receptors to provide therapeutic relief.

Interaction of Pivikto 150mg Tablet with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Pivikto 150mg tablet and reduce its effectiveness by causing undesirable side effects.

More Information about Pivikto 150mg Tablet

Regular monitoring of symptoms and follow-ups with your healthcare provider are recommended.

How to consume Pivikto 150mg Tablet

Your doctor will decide the dose and duration of Pivikto 150mg tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, immediately after food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water. If you cannot swallow the tablet, mix the tablets into a glass of water as per doctor advice.

Side Effects of Pivikto 150mg Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Pivikto 150 side effects are

Common

Hair loss

Decreased weight

Decreased appetite

Nausea, vomiting

Tiredness

Serious

Cellulitis

Hyperglycemia

Diarrhea

Hypersensitivity reactions

Pneumonitis

Dehydration

Angioedema

Safety Advice for Pivikto 150mg Tablet

Breast Feeding

Unsafe

Breastfeeding is not recommended in patients taking Pivikto 150mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.

Alcohol-Consult your doctor

Alcohol

Consult Your Doctor

It is not known whether it is safe to consume alcohol with Pivikto 150mg tablet. Please consult your doctor.

Liver-safe

Liver

Safe

Pivikto 150mg tablet is safe to use in patients with liver problems. There is no need for dose adjustments. Inform your physician if you have any liver disease before initiating the therapy.

Lungs-Consult your doctor

Lungs

Consult Your Doctor

It is unknown whether Pivikto 150mg tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Driving-safe

Driving

Safe

Pivikto 150mg tablet may alter your ability to drive and operate heavy machinery. The treatment may cause tiredness hence avoid activities after taking the medicine.

Pregnancy-unsafe

Pregnancy

Unsafe

Do not take Pivikto 150mg tablet if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for 1 week after the last dose.

Word of Advice for Pivikto 150mg Tablet

Your doctor may prescribe medicines to prevent nausea and vomiting before treatment. If you vomit after taking the tablet, take the next dose at the regular scheduled time. Women should use effective birth control during treatment and for 1 week after the last dose. Male patients with female partners should also use effective birth control during treatment and for 1 week after the last dose. Inform your doctor if you have kidney disease, lung disease, breathing problems, or diabetes. Do not breastfeed while on treatment and for 1 week after the last dose. Your doctor may recommend regular blood tests during treatment to monitor for unwanted side effects.

FAQs about Pivikto 150mg Tablet

Q1. Q1. Can a patient with kidney problems take Pivikto 150mg tablet?

Pivikto 150mg tablet should be cautiously taken if you have any kidney problems. Dose adjustments are necessary for patients with kidney diseases. Inform your doctor if you are on dialysis and have any kidney disorders.

Q2. Q2. What if I overdose or take two doses of Pivikto 150mg tablet?

If you unknowingly overdosed or took two doses of Pivikto 150mg tablet, immediately inform your healthcare professional and seek medical advice.

Q3. Q3. Should Pivikto 150mg tablet be taken with or without food?

Pivikto 150mg tablet comes as a tablet to take by mouth. It is usually taken immediately after the food. Take the tablets as prescribed by your doctor.

Q4. Q4. Does Pivikto 150mg tablet cause hair loss?

Thinning or loss of your hair will usually start within two to four weeks of your first dose of Pivikto 150mg tablet. You may also have thinning or loss of eyelashes, eyebrows, and other body hair. Consult your doctor if you have excessive hair loss.

Q5. Q5. Does Pivikto 150mg tablet cause an increase in sugar levels?

Pivikto 150mg tablet is intended to cause hyperglycemia because it blocks the intracellular action of insulin systemically. This mechanism of action creates a transient state of insulin resistance and hyperglycemia, a common adverse event observed.

Fact Box of Pivikto 150mg Tablet

Molecule Name	ALPELISIB
Marketer	NOVARTIS

References for Pivikto 150mg Tablet

1.Piqray 200 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Revised September 2022. Accessed April 28, 2023.
2.Piqray - alpelisib; Revised on 2019. Accessed April 28, 2023.
3.Kui-Jin Kim, et al., PI3K-targeting strategy using alpelisib to enhance the antitumor effect of paclitaxel in human gastric cancer, Scientific Reports, Jul 2020, [Accessed April 28, 2023]

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