Votrient 400mg Tablet

Prescription Required Cold Chain i

Salt Composition PAZOPANIB

Marketer NOVARTIS INDIA LTD

Prepaid Only. Non-Returnable.

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Introduction to Votrient 400mg Tablet

Votrient 400 mg tablet contains the active ingredient pazopanib, a cancer medicine that belongs to the class of drugs known as tyrosine kinase inhibitors. It is prescribed for adults to treat advanced kidney cancer that has spread to other parts of the body.
Do not take Votrient 400 mg if you are allergic to pazopanib or any of the other ingredients in this medicine. Before starting treatment, inform your doctor if you have any kidney, heart, liver, or lung conditions, bleeding problems, stomach or intestinal disorders, or thyroid issues. This medication may increase blood pressure, so regular monitoring is necessary during treatment. Dose adjustment is generally not required for patients with kidney impairment.
Your doctor may advise you to stop taking Votrient at least 7 days before any planned surgery or dental procedure, as it can interfere with wound healing. This medicine is not recommended for individuals under 18 years of age. It may also affect fertility, so discuss this risk with your doctor before starting treatment.
Common side effects include diarrhea, high blood pressure, changes in hair color, nausea, and vomiting

Uses of Votrient 400mg Tablet

Directly inhibits the growth and spread of cancer cells in conditions like advanced renal cell carcinoma.
Helps to reduce the size and impact of tumors in conditions such as soft tissue sarcoma.

Therapeutic Effects of Votrient 400mg Tablet

Votrient 400mg tablet is a biological agent that acts as targeted drug therapy in cancer treatment. It interferes with the growth of blood vessels inside the cancer cells by acting against a protein called Vascular Endothelial Growth Factors (VEGF) to shrink cancer cells, ultimately stopping their growth and multiplication.

Interaction of Votrient 400mg Tablet with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with the effects of Votrient 400mg tablet and reduce its effectiveness by causing undesirable side effects.

More Information about Votrient 400mg Tablet

Store Votrient 400mg tablet in room temperature (25°C) Keep the injection away from the reach of children and pets. If you forgot to take a dose, take it as soon as you remember. However, skip the missed dose if it is nearly time for the next dose. Take only a partial dose to make up for a forgotten dose.

How to consume Votrient 400mg Tablet

Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Take the tablets as prescribed by your doctor. Do not break, crush, or chew the tablets. Swallow the tablet whole with a glass of water. Do not take this medicine with food, as it affects the absorption of this medicine. Take Votrient 400mg tablet at least two hours after a meal or one hour before a meal.

Side Effects of Votrient 400mg Tablet

It is crucial to monitor any adverse effects and report them to your healthcare provider for appropriate management.

Common

Hypertension

Hair color change

Increased glucose levels

Decreased weight, decrease in appetite

Diarrhea

Nausea, vomiting

Muscle and joint pain

Headache

Shortness of breath

Tiredness

Serious

Heart problems

Bleeding from the anus, mouth

Hypothyroidism

Interstitial lung disease

Infections

Safety Advice for Votrient 400mg Tablet

Breast Feeding

Unsafe

Breastfeeding is not recommended in patients taking Votrient 400mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby.

Alcohol-Consult your doctor

Alcohol

Consult Your Doctor

It is unknown whether it is safe to consume alcohol when taking Votrient 400mg tablet. Consult your doctor for more advice.

Liver-unsafe

Liver

Unsafe

Votrient 400mg tablet is unsafe when administered in patients with severe liver diseases. Dose adjustments are necessary for moderate liver failure. Inform your physician if you have liver problems before initiating the therapy.

Lungs-Consult your doctor

Lungs

Consult Your Doctor

It is unknown whether Votrient 400mg tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Driving-unsafe

Driving

Unsafe

Driving or operating heavy machinery is unsafe after taking Votrient 400mg tablet because you may feel dizzy, drowsy, or have blurred vision.

Pregnancy-unsafe

Pregnancy

Unsafe

Votrient 400mg tablet is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for at least 2 weeks after your last dose is necessary.

Word of Advice for Votrient 400mg Tablet

Avoid consuming grapefruit juice while undergoing treatment with this medication, as it could heighten the risk of side effects. Male patients whose partners are of childbearing potential should use effective contraception during treatment and for at least two weeks after the final dose to prevent pregnancy. It is important to take the tablet consistently at the same time each day. Your doctor will conduct regular lab tests to monitor the effectiveness of the medication.

FAQs about Votrient 400mg Tablet

Q1. Q1. What is the correct way to take Votrient 400mg Tablet?

Votrient 400mg Tablet should be administered orally, once daily, or as prescribed by your healthcare provider. It is important to swallow the tablet whole with water and not to break or crush it, as altering the tablet can affect how the medication is absorbed and potentially increase side effects.

Q2. Q2. Can I take Votrient 400mg tablet of Votrient with food?

It is recommended that Votrient 400mg Tablet be taken on an empty stomach, either 1 hour before or 2 hours after eating. Consuming it with food could necessitate a higher dosage, which may lead to an increase in side effects.

Q3. Q3. Does Votrient 400mg tablet change hair color?

Hair color change is a common side effect of Votrient 400mg tablet therapy which usually develops gradually during a few months of therapy. Consult your doctor for more advice.

Q4. Q4. How can I tell if Votrient 400mg Tablet is effective?

The treatment duration with Votrient 400mg Tablet varies among individuals. Your doctor will conduct regular evaluations to determine the effectiveness of the treatment and decide how long you should continue taking it.

Q5. Q5. What are the benefits of Votrient 400mg tablet?

Votrient 400mg tablet is used to treat certain types of cancer (kidney, soft tissue sarcoma). It decreases the blood supply to the cancer tumor to slow tumor growth.

Fact Box of Votrient 400mg Tablet

Molecule Name	PAZOPANIB
Marketer	NOVARTIS INDIA LTD

References for Votrient 400mg Tablet

1.Highlights Of Prescribing Information - Pazopanib. [Revised on 2021] [cited 2023 Mar 24]. Available from:
2.Summary Of Product Characteristics - Pazopanib. [revised on 2021] [cited 2023 Mar 24]. Available from:
3.Votrient 400 mg film coated tablets - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. 2021 [cited 2023 Mar 24]
4.Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.

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Votrient 400mg Tablet

Introduction to Votrient 400mg Tablet

Uses of Votrient 400mg Tablet

Therapeutic Effects of Votrient 400mg Tablet

Interaction of Votrient 400mg Tablet with other drugs

More Information about Votrient 400mg Tablet

How to consume Votrient 400mg Tablet

Side Effects of Votrient 400mg Tablet

Safety Advice for Votrient 400mg Tablet

Word of Advice for Votrient 400mg Tablet

FAQs about Votrient 400mg Tablet

Fact Box of Votrient 400mg Tablet

References for Votrient 400mg Tablet

Why MedXtra?

THE MEDXTRA CHECK: VERIFIED GENUINE MEDICINES AT THE BEST PRICES EVER