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Home โ€บ Medicine โ€บ Tepmetko 225mg Tablet
Substitutes

Tepmetko 225mg Tablet

Prescription Required Cold Chain i
Salt Composition TEPOTINIB
Marketer MERCK LTD
Prepaid Only. Non-Returnable.
?
This medicine is prepaid
only and cannot be
returned once delivered.
6% OFF
We are Rated 4.8 On Google

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8h 12m 27s

Introduction to Tepmetko 225mg Tablet

Tepmetko 225mg Tablet contains the active ingredient Tepotinib. It is primarily used to slow or stop the growth of cancer cells and prevent their spread, especially in patients with non-small cell lung cancer (NSCLC) that carry a mutation in the MET gene.

One advantage of Tepmetko 225mg Tablet is that it may cause fewer side effects compared to traditional chemotherapy. However, it can still lead to side effects such as nausea, vomiting, and fatigue.

Precautions:

Do not take Tepmetko 225mg Tablet if you are allergic to it or any of its ingredients.

Patients with a history of heart, kidney, lung, or liver problems should consult their doctor before starting treatment.

Its safety in elderly patients has not been fully established, so close monitoring is advised in this population.

During treatment, patients are monitored for signs of bleeding, including coughing up blood (hemoptysis), dark, tarry stools (melena), or severe bleeding leading to shock.

Avoid consuming large amounts of grapefruit or grapefruit juice, as it can increase the risk of side effects or interactions with other medications.

Uses of Tepmetko 225mg Tablet

Treatment of non-small cell lung cancer (NSCLC)

Therapeutic Effects of Tepmetko 225mg Tablet

In patients with NSCLC and the specific MET mutation, Tepmetko 225mg Tablet has been shown to have an anti-tumor effect, leading to tumor shrinkage and improved disease control. Studies have demonstrated that this medicine can significantly improve progression-free survival (PFS) in patients with NSCLC compared to standard chemotherapy.

Interaction of Tepmetko 225mg Tablet with other drugs

Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Tepmetko 225mg Tablet, reducing effectiveness by causing undesirable side effects.

More Information about Tepmetko 225mg Tablet

Store in a refrigerator between 20-25ยฐC (68-77ยฐF). Keep away from moisture, heat, and light. It should not be frozen. Keep it in its original packaging until it is ready to be used. Keep out of the reach of children and pets.

How to consume Tepmetko 225mg Tablet

Take Tepmetko 225mg Tablet exactly as your doctor prescribes. The recommended dose and dosing schedule may vary depending on your medical condition, age, weight, and other factors. It should be taken with food. Swallow the tablet as a whole with a glass of water. Patients should not chew, crush, or break the tablet, as this may affect the effectiveness of the medication. Avoid doubling the dose to compensate for the missed dose.

Side Effects of Tepmetko 225mg Tablet

Tepmetko 225mg Tablet cause some side effects like all medications, although not everyone will experience them.
Serious:
Hepatotoxicity
Interstitial lung disease (ILD)
Severe skin reactions
Perforation or fistula formation in the gastrointestinal tract
Bleeding, including severe or fatal bleeding
Common:
Edema (swelling)
Nausea
Diarrhea
Fatigue
Anorexia (loss of appetite)
Vomiting
Increased blood creatinine levels
Increased alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels
Rash or itching
Muscle pain or weakness

Safety Advice for Tepmetko 225mg Tablet

Breast Feeding
Consult Your Doctor
It is unknown if Tepmetko 225mg Tablet is excreted in human breast milk, so breastfeeding women should consult a healthcare provider before taking this medication.
Alcohol-unsafe
Alcohol
Unsafe
Individuals should avoid consuming alcohol before or immediately after receiving Tepmetko 225mg Tablet, as alcohol can impair the immune system and potentially reduce the effectiveness of the treatment.
Liver-unsafe
Liver
Unsafe
Tepmetko 225mg Tablet can cause liver toxicity, so it should be avoided in patients who have severe liver disease.
Lungs-unsafe
Lungs
Unsafe
Tepmetko 225mg Tablet can cause lung problems, such as interstitial lung disease (ILD) or pneumonitis. Patients with a history of lung disease or pre-existing lung damage may be at increased risk for these side effects.
Driving-unsafe
Driving
Unsafe
Patients should always monitor their response to the Tepmetko 225mg Tablet medication and be cautious when driving or operating machinery if they experience any side effects that may impair their ability to do so safely.
Pregnancy-Consult your doctor
Pregnancy
Consult Your Doctor
Pregnant women should consult their healthcare provider about their pregnancy status before receiving Tepmetko 225mg Tablet.

Word of Advice for Tepmetko 225mg Tablet

If you have been prescribed Tepmetko 225mg Tablet, it is important to follow your doctor's instructions carefully. Suppose you experience any unusual symptoms or side effects while taking Tepmetko 225mg Tablet, such as fever, persistent cough, difficulty breathing, abdominal pain, or signs of liver dysfunction. In such a case, you should contact your doctor immediately. Do not stop medication without first consulting your doctor, as this may affect the effectiveness of the medication and your treatment outcomes. Pregnant and breastfeeding women should consult with a healthcare provider before taking it. Avoid close contact with an infected person, as this medication lowers the immune system. Always maintain a healthy and balanced diet to support your overall health and well-being.

FAQs about Tepmetko 225mg Tablet

Q1. Q1. Can Tepmetko 225mg Tablet cause high blood pressure?

Yes, Tepmetko 225mg Tablet can cause or worsen pre-existing hypertension. Patients receiving this medicine should monitor their blood pressure regularly during treatment, and antihypertensive medications may be necessary to control hypertension.

Q2. Q2. What are the potential skin reactions associated with Tepmetko 225mg Tablet?

Tepmetko 225mg Tablet can cause severe skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis. Patients should be monitored for skin rash, blistering, or peeling, and treatment should be discontinued if severe skin reactions occur.

Q3. Q3. Can Tepmetko 225mg Tablet affect renal function?

Yes, Tepmetko 225mg Tablet may cause renal impairment, and patients with pre-existing renal impairment may be at an increased risk of developing renal toxicity. Patients should have their renal function monitored regularly during treatment.

Q4. Q4. Is there a risk of cataracts with Tepmetko 225mg Tablet?

Yes, there is a potential risk of developing cataracts using Tepmetko 225mg Tablet. Patients receiving it should check their vision regularly during treatment, and treatment should be discontinued if cataracts develop.

Q5. Q5. Can Tepmetko 225mg Tablet affect fertility?

There is currently no information on whether Tepmetko 225mg Tablet affects human fertility. However, animal studies have shown that this medication may cause reversible testicular toxicity in male rats. Patients who are planning to have children or are experiencing fertility problems should discuss their concerns with their healthcare provider before starting treatment.

Fact Box of Tepmetko 225mg Tablet

Molecule Name TEPOTINIB
Marketer MERCK LTD

References for Tepmetko 225mg Tablet

1.Merck Limited, Electronic Medicines Compendium (EMC), [Revised on 25 May 2022] [Accessed on 10th May 2023],
2.EMD Serono, Inc., US Food & Drug Administration, [Revised on 3rd Feb 2021] [Accessed on 10th May 2023],
3.Goodman & Gilman's the pharmacological basis of Therapeutics, 13th Edition., 2018, 1549-1674
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Tepmetko 225mg Tablet
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