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Home › Medicine › Staurinz 25mg Capsule
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Staurinz 25mg Capsule

Prescription Required Cold Chain i
Salt Composition MIDOSTAURIN
Marketer DR REDDY'S
Prepaid Only. Non-Returnable.
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Introduction to Staurinz 25mg Capsule

Staurinz 25 mg Capsule contains the active ingredient midostaurin. It is an anti-cancer medication that belongs to the class of drugs called tyrosine kinase inhibitors. This medicine is used in combination with other chemotherapy drugs to treat acute myeloid leukemia (AML) in adults with a genetic mutation in the FLT3 gene. AML is a type of blood cancer in which the body produces an excessive number of abnormal myeloid white blood cells.

Staurinz 25 mg Capsule is also prescribed for adults with aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematological neoplasm (SM-AHN), or mast cell leukemia (MCL).

Do not take this medicine if you are allergic to midostaurin or any of its ingredients. Inform your doctor if you have signs of infection, heart problems, lung disease, or breathing difficulties. Seek medical attention immediately if you experience symptoms such as fever, sore throat, mouth ulcers, cough (with or without mucus), chest pain, shortness of breath, or swelling in any part of the body during treatment.

This medicine is not recommended for children or adolescents under 18 years of age. Before starting treatment, tell your doctor if you are pregnant, breastfeeding, or planning to become pregnant. Staurinz may affect fertility in both men and women, so discuss this with your doctor before beginning therapy.

The most common side effects of Staurinz 25 mg Capsule include fever with reduced blood cell counts, nausea, vomiting, headache, muscle or joint pain, increased blood sugar levels, and respiratory infections.

Uses of Staurinz 25mg Capsule

Acute myeloid leukemia (AML)
Aggressive systemic mastocytosis (ASM)
Systemic mastocytosis with associated hematological neoplasm (SM-AHN)
Mast cell leukemia (MCL)

Therapeutic Effects of Staurinz 25mg Capsule

Staurinz 25mg capsule is a kinase inhibitor that potently inhibits multiple receptor tyrosine kinases. It blocks the action of the kinases in the abnormal cells that express FLT3 mutant genes and stops their division and growth.

Interaction of Staurinz 25mg Capsule with other drugs

Inform your healthcare provider about all the medicines you are taking, including prescription medications, over-the-counter medications, vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications may interact with the effects of Staurinz 25mg capsule and reduce its effectiveness by causing undesirable side effects.

More Information about Staurinz 25mg Capsule

Store Staurinz 25mg capsule at room temperature (25°C) keep the capsule away from the reach of children and pets. If you miss a dosage, take it as soon as you remember. If it is almost time for the next dose, skip the missing dose. Do not take a double dose to compensate for a missed dose.

How to consume Staurinz 25mg Capsule

Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Take the Staurinz 25mg capsule as prescribed by your doctor. Do not open, break, crush, or chew the capsules. Swallow the capsule whole with a glass of water. Take the capsules with food at the same time each day.

Side Effects of Staurinz 25mg Capsule

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
Swelling in the lower limbs
Skin rash
Increased blood sugar levels
Abdominal pain
Constipation, diarrhea
Nausea, vomiting
Musculoskeletal pain
Headache
Bleeding from nose
Upper respiratory infection
Tiredness
Fever
Serious
Heart failure
GI bleeding
Fever with decreased blood cell counts
Hypersensitivity reactions
Kidney problems
Pneumonia
Blood infection

Safety Advice for Staurinz 25mg Capsule

Breast Feeding
Unsafe
Breastfeeding is not recommended in patients taking Staurinz 25mg capsule because the medicine passes into the breast milk in small amounts and may harm the baby.
Alcohol-unsafe
Alcohol
Unsafe
It is unsafe to consume alcohol when taking Staurinz 25mg capsule because it may cause alcohol-related problems, epilepsy, or liver problems.
Liver-unsafe
Liver
Unsafe
Staurinz 25mg capsule should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary for severe liver failure. Inform your physician if you have liver problems before initiating the therapy.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
It is unknown whether Staurinz 25mg capsule can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Driving-unsafe
Driving
Unsafe
Driving vehicles or operating machinery after taking Staurinz 25mg capsule is unsafe as you may develop dizziness and vertigo.
Pregnancy-unsafe
Pregnancy
Unsafe
Staurinz 25mg capsule is unsafe to administer in pregnant women because it may cause birth defects. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using effective contraception during the treatment and for at least 4 months after your last dose is necessary.

Word of Advice for Staurinz 25mg Capsule

Do not breastfeed during the treatment with Staurinz 25mg capsule and for at least 4 months after the last dose. Avoid grapefruit juice during the treatment with this medicine. If you vomit after taking this medicine, do not take another capsule to make up the dose. If you are a male patient with a female partner with reproducing potential, use effective contraception during the treatment and for 4 months after the last dose. Your doctor will perform regular blood tests during the treatment to monitor the number of blood cells and electrolytes in your body. Your heart and lung function will also be checked regularly. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury.

FAQs about Staurinz 25mg Capsule

Q1. Q1. What are the cautions of Staurinz 25mg capsule?

Tell your doctor immediately if you start to have swelling of your face, lower limbs or skin, fever, sore throat, mouth ulcers, cough with or without mucous, chest pain or discomfort, trouble breathing, shortness of breath, light-headedness, fainting, dizziness, blue discoloration of your lips, hands or feet.

Q2. Q2. Can Staurinz 25mg capsule cause vomiting?

Yes, Staurinz 25mg capsule has a moderate emetic effect and can cause vomiting. Do not take an extra capsule if you have vomited after taking your first dose.

Q3. Q3. Does Staurinz 25mg capsule cause hair loss?

No, hair loss is not a side effect of Staurinz 25mg capsule. Hair loss can happen due to cancer itself. Consult your doctor if you have excessive hair loss.

Q4. Q4. How will I be monitored during the treatment with Staurinz 25mg capsule?

Your doctor will perform regular blood tests during treatment with Rydapt in order to monitor the number of blood cells (white blood cells, red blood cells, and platelets) and electrolytes such as calcium, potassium, and magnesium in your body. Your heart and lung function will also be checked regularly.

Q5. Q5. How long does it take Staurinz 25mg capsule to work?

Staurinz 25mg capsule is a long-term treatment. Most people who benefit from this treatment will notice an improvement in the first 12 weeks of starting treatment.

Q6. Q6. What will happen if I stop taking Staurinz 25mg capsule suddenly?

Stopping your treatment suddenly may cause your condition to become worse. Do not stop taking your medicine without consulting your doctor.

Fact Box of Staurinz 25mg Capsule

Molecule Name MIDOSTAURIN
Marketer DR REDDY'S

References for Staurinz 25mg Capsule

1.Novartis Pharmaceuticals, Electronic Medicines Compendium (EMC), www.medicines.org.uk. [revised on 2022] [cited 2023 Apr 13]. Available from:
2.Novartis Pharmaceuticals, Highlights Of Prescribing Information, Midostaurin, [revised on 2017] [cited 2023 Apr 13]. Available from
3.Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.
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Staurinz 25mg Capsule
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Inclusive of all taxes 22% OFF
(You Save ₹5,649.06)
28 Cap Capsule in Box

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