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Home β€Ί Medicine β€Ί Prevall Oral Suspension
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Prevall Oral Suspension

Prescription Required Cold Chain i
Salt Composition MERCAPTOPURINE
Marketer Salt Composition MERCAPTOPURINE
Prepaid Only. Non-Returnable.
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This medicine is prepaid
only and cannot be
returned once delivered.
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Introduction to Prevall Oral Suspension

Prevall Oral Suspension is an anticancer medication that belongs to the class of purine antagonists and contains the active ingredient mercaptopurine. It is primarily used in the treatment of acute lymphoblastic leukemia (ALL), a type of cancer that affects the blood and bone marrow. In ALL, immature white blood cells called lymphoblasts are produced in excess, fail to function properly, and accumulate in the blood and bone marrow.

If you are scheduled for a vaccination, consult your doctor or nurse beforehand. While taking this medication, live vaccines (such as polio, measles, mumps, and rubella) should be avoided unless your doctor confirms it is safe. The yellow fever vaccine should not be taken during treatment, as it can cause serious illness.

Your doctor may request regular blood and urine tests to monitor kidney function and measure uric acid levels. Mercaptopurine can increase uric acid, which may damage the kidneys. Dosage adjustments may be needed based on these test results. Patients with impaired kidney or liver function may require lower starting doses due to slower drug elimination and increased cumulative effects.

During therapy, your doctor will likely monitor white blood cell counts, platelets, blood sugar, electrolytes, and kidney function to prevent complications. Inform your doctor if you have a history of liver disorders, heart failure, high cholesterol, or hypertension before starting treatment. Mercaptopurine may affect liver function, so weekly liver function tests are usually recommended.

Report any signs of allergic reactions, such as itching or rashes, while taking this medicine. This oral suspension contains lactose as an inactive ingredient. If you are lactose intolerant, you may experience bloating, abdominal pain, or other digestive symptoms, and you should inform your doctor before starting therapy.

Uses of Prevall Oral Suspension

Acute lymphoblastic leukaemia

Therapeutic Effects of Prevall Oral Suspension

It works by interfering with the DNA and RNA function in cancer cells, inhibiting nucleotide synthesis, suppressing the immune system, and activating enzymes that can kill cancer cells. It is usually used in combination with other chemotherapy drugs to increase its effectiveness.

Interaction of Prevall Oral Suspension with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Prevall Oral Suspension and reduce effectiveness by causing undesirable side effects.

More Information about Prevall Oral Suspension

Store Prevall Oral Suspension in the original package at room temperature (15Β°C to 25Β°C). Keep it out of reach from children.

How to consume Prevall Oral Suspension

Prevall Oral Suspension is typically consumed orally as directed by your doctor or healthcare professional. Shake the suspension well before use to ensure proper mixing of the ingredients. Measure the medicine properly. Follow your doctor or healthcare professional's instructions regarding the recommended dosage and administration. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the granules if your doctor advises you to stop.

Side Effects of Prevall Oral Suspension

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
Nausea, vomiting
Anemia
Fever or infection (sore throat, sore mouth, or urinary problems)
Unexplained bruising or bleeding
Low white blood cell and platelet count

Safety Advice for Prevall Oral Suspension

Breast Feeding
Unsafe
Prevall Oral Suspension should not be taken if you are breastfeeding as it passes into breast milk. You need to tell your physician if you are breastfeeding before taking this medicine.
Alcohol-unsafe
Alcohol
Unsafe
Consuming alcohol may affect the effectiveness of Prevall Oral Suspension. Stop consuming alcohol if you are taking this medicine.
Liver-Consult your doctor
Liver
Consult Your Doctor
Inform your doctor if you have any liver problems before taking Prevall Oral Suspension. Regular monitoring of liver function tests is recommended.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
It is not known whether Prevall Oral Suspension can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Driving-unsafe
Driving
Unsafe
It is unsafe to drive vehicles or operate heavy machinery after taking Prevall Oral Suspensions, it may cause dizziness and impair your concentration.
Pregnancy-Consult your doctor
Pregnancy
Consult Your Doctor
Prevall Oral Suspension is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Word of Advice for Prevall Oral Suspension

It is advised to consult the physician if you experience fever, sore throat, jaundice, nausea, vomiting, signs of local infection, bleeding from any site, or symptoms suggestive of anaemia. Women of childbearing potential should be advised to avoid becoming pregnant. It is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment. This medicine passes into the breast milk. Hence, it is not recommended to breastfeed during this treatment. It is recommended to limit your alcohol intake or avoid it altogether during the treatment. While you are taking this drug, you are more sensitive to the sun and UV light. Just make sure to limit your exposure to sunlight and UV light, wear protective clothing and use a sun cream with a high sun protection factor (SPF). Low blood sugar (sweating more than usual, nausea, dizziness, confusion, etc.) has sometimes been seen in children, mainly in children under the age of six or with a low body mass index. Talk to your child's doctor if this happens.

FAQs about Prevall Oral Suspension

Q1. Q1. What happens if you take Prevall Oral Suspension with milk?

Taking Prevall Oral Suspension with milk may decrease the absorption and effectiveness of the medication. This is because the calcium in milk can bind to Prevall Oral Suspension, forming an insoluble complex that reduces the amount of the medicine that can be absorbed by the body.

Q2. Q2. Can I drink alcohol while taking Prevall Oral Suspension?

It is generally advised to avoid drinking alcohol while taking Prevall Oral Suspension, as alcohol can increase the risk of liver damage.

Q3. Q3. What is the complication of Prevall Oral Suspension?

Prevall Oral Suspension can also cause more serious complications, such as bone marrow suppression, which can lead to decreased production of blood cells and an increased risk of infections, bleeding, and anaemia.

Q4. Q4. What you should know while taking Prevall Oral Suspension?

You should have caution while taking this medicine, it can cause liver problems like jaundice, hepatomegaly and anorexia.

Fact Box of Prevall Oral Suspension

Molecule Name MERCAPTOPURINE
Marketer Salt Composition MERCAPTOPURINE

References for Prevall Oral Suspension

1.Aspen Pharma Trading Limited, Electronic medicines compendium (emc), [ Revised on August 2019] (Accessed: April 6, 2023),
2.DSM Pharmaceuticals, Inc., US Food and Drug Administration, [Accessed on 15th Jan 2022]
3.Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1701 - 1702.
4.KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013.
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Prevall Oral Suspension
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