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Home β€Ί Medicine β€Ί Lupride Depot 45mg Injection

Lupride Depot 45mg Injection

Prescription Required Cold Chain i
Salt Composition LEUPROLIDE ACETATE
Marketer SUN PHARMACEUTICAL INDUSTRIES LTD
Prepaid Only. Non-Returnable.
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This medicine is prepaid
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returned once delivered.
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Introduction to Lupride Depot 45mg Injection

Lupride Depot 45mg Injection contains the active ingredient Leuprolide acetate and belongs to a class of medications called Gonadotropin-Releasing Hormone (GnRH) agonists. This injection is used to treat:

Prostate cancer in men

Hormone-responsive breast cancer, endometriosis (when uterine tissue grows outside the uterus), and uterine fibroids (noncancerous uterine growths) in women

Precocious puberty (early onset of puberty in children due to hormonal imbalance)

Do not receive Lupride Depot 45mg Injection if you are allergic to Leuprolide acetate or any of the other ingredients, including Goserelin or Triptorelin.

Before starting treatment, inform your doctor if you:

Have liver or kidney problems

Have undiagnosed abnormal uterine bleeding

Are pregnant or planning to become pregnant

During treatment, symptoms may temporarily worsen due to changes in sex hormone levels. If your child has a progressive brain tumor, inform your doctor immediately.

Also notify your doctor if you have underlying health conditions such as:

Diabetes

Seizures

Heart problems, including chest pain or irregular heartbeats

Depression

Risk of osteoporosis (bone thinning)

This medicine is not recommended for patients with abnormal vaginal bleeding. Women of childbearing age should use non-hormonal contraception while on treatment.

Men should inform their doctor if they have urinary obstruction or have had a surgical removal of the testicles. Report immediately if you experience spinal cord pressure, urinary problems, or blood in the urine (haematuria).

Uses of Lupride Depot 45mg Injection

Prostate cancer
Hormone-responsive breast cancer in perimenopausal (around menopause) women
Endometriosis (a painful illness in which the tissue that normally lines the inside of the uterus grows outside of your uterus)
Central precocious puberty (a child’s body begins to change into an adult too soon caused by a release of certain hormones)

Therapeutic Effects of Lupride Depot 45mg Injection

Lupride Depot 45mg Injection decreases testosterone or estrogen production, depending on the treated condition. This helps to slow the growth of cancer cells, reduce the size of uterine fibroids, and alleviate the symptoms of endometriosis and early onset of puberty.

Interaction of Lupride Depot 45mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional and vitamin supplements, vaccines, and herbal products. Certain medications such as Quinidine, Procainamide, Amiodarone, Sotalol, Pain killers, and Antibiotics may interact with the effects of Lupride Depot 45mg Injection and reduce its effectiveness by causing undesirable side effects.

More Information about Lupride Depot 45mg Injection

Keep Lupride Depot 45mg Injection out of sight and reach of children. Store in a cool, dry place, away from direct heat and light. Store below 25Β°C Do not refrigerate or freeze.

How to consume Lupride Depot 45mg Injection

Lupride Depot 45mg injection is usually administered in the arm, thigh or abdomen. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.

Side Effects of Lupride Depot 45mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
Severe rash, itching
Shortness or difficulty of breath
Cough with blood
Pulmonary embolism
Severe headache
Common
Altered blood sugar and cholesterol levels
Injection site reactions
Loss of appetite
Abnormal liver function
Swelling in the ankle or hand
Difficulty sleeping, headache
Mood swings, depression
Weight changes
Nausea, vomiting
Vaginal dryness, bleeding
Loss of interest in sexual intercourse
Hot flushes
Bone pain, muscle weakness
Breast tenderness

Safety Advice for Lupride Depot 45mg Injection

Breast Feeding
Unsafe
Lupride Depot 45mg injection is contraindicated in breastfeeding women. Inform your doctor if you are breastfeeding before taking this injection.
Alcohol-unsafe
Alcohol
Unsafe
Consuming alcohol during the Lupride Depot 45mg injection treatment may increase the risk of thinning bones (osteoporosis). Hence caution should be taken. Consult your doctor for more information
Liver-unsafe
Liver
Unsafe
Lupride Depot 45mg Injection should be used cautiously in patients with liver impairment. Consult your doctor before receiving it. Notify your doctor about underlying liver conditions.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
It is unknown whether Lupride Depot 45mg Injection is safe for patients with lung problems. Notify your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Driving-unsafe
Driving
Unsafe
Lupride Depot 45mg Injection can cause drowsiness, visual disturbances, or dizziness. It is unsafe; hence avoid driving if you are unwell.
Pregnancy-unsafe
Pregnancy
Unsafe
It is unsafe to use Lupride Depot 45mg injection because it is contraindicated in pregnant women. Tell your doctor if you are pregnant or planning to get pregnant before taking this treatment.

Word of Advice for Lupride Depot 45mg Injection

During the treatment of breast cancer with Lupride Depot 45mg Injection, it is recommended to undergo regular checkups every three months in combination with an aromatase inhibitor. Do not receive this injection if you experience any abnormal vaginal bleeding. Consult your doctor immediately if you or your child is suffering from a headache even after treating it with painkillers, vision problems, buzzing, or ringing in the ear. If you have diabetes, ask your doctor to monitor your glucose and blood sugar levels regularly. Before starting, inform your doctor if you are still mensurating.

FAQs about Lupride Depot 45mg Injection

Q1. Q1. What is the working mechanism of Lupride Depot 45mg Injection?

Lupride Depot 45mg Injection decreases testosterone or estrogen production, depending on the treated condition. This helps to slow the growth of cancer cells, reduce the size of uterine fibroids, and alleviate the symptoms of endometriosis and early onset of puberty.

Q2. Q2. Who should not use Lupride Depot 45mg Injection?

Lupride Depot 45mg Injection should not be used by pregnant and breastfeeding women, people who are allergic to the medication, or people with a history of osteoporosis or bone fractures. It should also be used cautiously in people with a past of depression or mental illness.

Q3. Q3. What should I do if I miss a dose of Lupride Depot 45mg Injection?

If you miss a dose of Lupride Depot 45mg Injection, contact your healthcare provider as soon as possible to schedule the missed dose. Do not double up on doses to make up for a missed one.

Q4. Q4. Can Lupride Depot 45mg Injection cause weight gain?

Weight gain is not a common side effect of Lupride Depot 45mg Injection, but it may occur in some people.

Q5. Q5. What are the benefits of Lupride Depot 45mg Injection in managing endometriosis?

Lupride Depot 45mg Injection reduces estrogen production and helps relieve endometriosis symptoms by inhibiting tissue growth outside the uterus.

Fact Box of Lupride Depot 45mg Injection

Molecule Name LEUPROLIDE ACETATE
Marketer SUN PHARMACEUTICAL INDUSTRIES LTD

References for Lupride Depot 45mg Injection

1.Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Introduction to Endocrinology: The hypothalamic-pituitary axis, 12th edition, 2011, 1122.
2.KD Tripathi, Essentials of Medical Pharmacology, Anterior pituitary hormones, 7th edition, 2013, 243.
3.Takeda UK Limited, Electronic medicines compendium (emc), [ Revised on June 2022] [ Accessed on 12th April 2023],
4.Abbott Laboratories, US Food and Drug Administration, [Issued on Feb 2016]
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Lupride Depot 45mg Injection
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