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Home › Medicine › Hemlibra 105mg Injection
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Hemlibra 105mg Injection

Prescription Required Cold Chain i
Salt Composition EMICIZUMAB
Marketer ROCHE PRODUCTS INDIA
Prepaid Only. Non-Returnable.
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Introduction to Hemlibra 105mg Injection

Hemlibra 105 mg Injection contains the active ingredient emicizumab and belongs to a class of medicines known as monoclonal antibodies. It is used to treat patients with haemophilia A who have developed factor VIII inhibitors, as well as those with severe haemophilia A who have not developed factor VIII inhibitors (with factor VIII blood levels below 1%).

Haemophilia A is an inherited bleeding disorder caused by a deficiency of factor VIII, a protein essential for normal blood clotting. Monoclonal antibodies are specialized proteins that bind to specific targets in the body. Hemlibra helps prevent bleeding episodes or reduces their frequency in patients with haemophilia A.

Do not use Hemlibra 105 mg Injection if you are allergic to emicizumab or any of the other ingredients. Before starting this medication, inform your doctor about all other medicines you are taking. Contact your healthcare provider immediately if bleeding occurs while using this injection.

This medicine can be used in patients of all age groups. The injection should not be administered into areas where the skin is red, bruised, tender, hardened, or has moles or scars.

Uses of Hemlibra 105mg Injection

Hemophilia A

Therapeutic Effects of Hemlibra 105mg Injection

Emicizumab binds to activated factor IX and factor X to restore function to the coagulation cascade and promote hemostasis. It restores the function of missing activated factor VIII, which is needed for effective blood clotting. Its structure differs from factor VIII; therefore, the medicine is unaffected by factor VIII inhibitors.

Interaction of Hemlibra 105mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Hemlibra 105mg Injection and reduce its effectiveness by causing undesirable side effects.

More Information about Hemlibra 105mg Injection

Store in a refrigerator (2°C to 8°C) Do not freeze Protect the medicine from light and excessive moisture. Keep the medicine out of reach of children and pets If you missed the dosing schedule, inform your healthcare professional immediately and reschedule.

How to consume Hemlibra 105mg Injection

Hemlibra 105mg injection will be given under the skin (subcutaneous). Your doctor, nurse, or other healthcare professional will show you how to inject the medicine. Do not try to administer the medicine if you are well-trained. Your physician will decide the dose of the injection based on your disease condition and severity. The recommended places to give an injection are the front of the waist (lower abdomen), upper outer arms, or the front of the thighs. Use only recommended places for injection. For each injection, use a different area of the body than the one you used last time.

Side Effects of Hemlibra 105mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
Injection site reactions
Joint pain
Headache
Serious
Heart problems
Muscle cramps and pain
Blood clot
Bleeding
Destruction of red blood cells

Safety Advice for Hemlibra 105mg Injection

Breast Feeding
Unsafe
Breastfeeding is not recommended in patients taking Hemlibra 105mg Injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Alcohol-Consult your doctor
Alcohol
Consult Your Doctor
It is unknown whether it is safe to consume alcohol with Hemlibra 105mg Injection. Inform your physician if you are a chronic drinker.
Liver-safe
Liver
Safe
It is safe to administer Hemlibra 105mg Injection in patients with liver problems. No dose adjustments are needed for mild to moderate impairment. However, Inform your physician if you have any liver diseases before initiating the treatment.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
It is unknown whether Hemlibra 105mg Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Driving-safe
Driving
Safe
Hemlibra 105mg Injection does not affect your ability to drive and operate heavy machinery. Inform your physician if you face any symptoms that alter your concentration.
Pregnancy-unsafe
Pregnancy
Unsafe
Do not take Hemlibra 105mg Injection if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for 6 months after the last dose.

Word of Advice for Hemlibra 105mg Injection

This medicine is given as a shot under your skin. It is usually injected into the upper outer arms, thighs, or stomach. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. Do not inject into skin areas that are tender, red, bruised, hard, or not intact, or into areas with moles or scars. Use a new needle and syringe each time you inject your medicine. Women should use an effective form of birth control to keep from getting pregnant. Tell your doctor right away if you think you have become pregnant. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments

FAQs about Hemlibra 105mg Injection

Q1. Q1. Can Hemlibra 105mg Injection be self-administered at home?

Yes, Hemlibra 105mg Injection can be self-administered at home after proper training and instructions from a healthcare professional. However, the decision to self-administer should be made in consultation with the healthcare team.

Q2. Q2. Can Hemlibra 105mg Injection be used in pediatric patients with hemophilia?

es, Hemlibra 105mg Injection is approved for use in pediatric patients with hemophilia A. The dosage and administration may vary depending on the age and weight of the child, and it should be prescribed and monitored by a healthcare professional.

Q3. Q3. Is Hemlibra 105mg Injection suitable for all types of hemophilia?

Hemlibra 105mg Injection is specifically designed for the treatment of hemophilia A, which is caused by a deficiency of clotting factor VIII. It is not intended for other types of hemophilia, such as hemophilia B.

Q4. Q4. How is Hemlibra 105mg Injection administered?

Hemlibra 105mg Injection is administered as a subcutaneous injection, generally, it is given once a week, every two weeks, or every four weeks, depending on the treatment plan determined by the healthcare provider. The frequency of the administration depends on your disease condition and other factors.

Q5. Q5. What should I inform the physician before starting the treatment with Hemlibra 105mg Injection?

Before you start using Hemlibra 105mg Injection, talk to your doctor and carefully follow their instructions on when to use a bypassing agent and the dose and schedule you should use. It increases the ability of your blood to clot. Therefore, the dose of bypassing agent required may be lower than the dose you used before starting Hemlibra.

Fact Box of Hemlibra 105mg Injection

Molecule Name EMICIZUMAB
Marketer ROCHE PRODUCTS INDIA

References for Hemlibra 105mg Injection

1.Hemlibra 150 mg/mL Solution for Injection - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published September 2022. Accessed May 10, 2023.
2.Emicizumab Injection, Highlights of Prescribing Information, Revised 2017. Accessed May 10, 2023.
3.H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056.
4.Le Quellec, Clinical Evidence and Safety Profile of Emicizumab for the Management of Children with Hemophilia A, Drug Design, Development and Therapy, 2020:14
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