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Home › Medicine › Grastim 300mcg Injection
Substitutes

Grastim 300mcg Injection

Prescription Required Cold Chain i
Salt Composition FILGRASTIM
Marketer DR REDDY'S LABORATORIES LTD
Prepaid Only. Non-Returnable.
?
This medicine is prepaid
only and cannot be
returned once delivered.
51% OFF
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Introduction to Grastim 300mcg Injection

Grastim 300mcg Injection contains filgrastim as its active ingredient. This medication is a white blood cell growth factor, specifically a granulocyte-colony stimulating factor. It has received FDA approval for several critical uses:

Reducing Febrile Neutropenia Risk: It helps lower the chance of developing febrile neutropenia (fever or infection linked to a low white blood cell count) in individuals with non-myeloid cancer undergoing chemotherapy.
Shortening Neutropenia Duration: It also reduces the length of time neutropenia (a low white blood cell count) persists in these patients.
Acute Myeloid Leukemia (AML): Grastim is used to increase the number of white blood cells and decrease the duration of fever in individuals with AML.
Bone Marrow Transplants: It is administered to patients undergoing bone marrow transplants.
Severe Chronic Neutropenia: It is also used to treat individuals with severe chronic neutropenia (a persistently low number of neutrophils in the blood).
Leukapheresis Preparation: Grastim 300mcg Injection is employed to prepare the blood for leukapheresis, a procedure where specific blood cells are removed.
Radiation Exposure: It is indicated to improve survival chances for individuals exposed to dangerous levels of radiation, which can severely damage bone marrow.
Advanced HIV Infection: In patients with advanced HIV infection, it helps to lower the risk of developing infections.

Grastim 300mcg Injection falls under the category of medications known as colony-stimulating factors. These medications function by stimulating the body to produce more white blood cells (WBCs). WBCs are vital for your body's defense against infections. Chemotherapy can significantly impact WBCs, potentially causing a reduction in their numbers. A low WBC count can compromise your body's ability to fight off bacteria, increasing your susceptibility to infection.
Please inform your doctor if you have a history of or currently have liver disease, kidney problems, sickle cell anemia, or any bone disease. Common side effects that may occur include fever, pain, rash, cough, shortness of breath, and nosebleeds.

Uses of Grastim 300mcg Injection

To prevent infections after chemotherapy due to decreased white blood cells (neutropenia)

Therapeutic Effects of Grastim 300mcg Injection

Grastim 300mcg injection is a colony-stimulating factor that acts on blood-forming cells by binding to specific cell surface receptors, thereby inducing cell division, multiplication, and cell functional activation.

Interaction of Grastim 300mcg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Grastim 300mcg injection and reduce effectiveness by causing undesirable side effects.

More Information about Grastim 300mcg Injection

Store Grastim 300mcg injection in a refrigerator (2°C – 8°C). Do not freeze. Do not shake the pre-filled syringe. Discard the medicine if stored at room temperature for more than 48 hours. Keep it out of reach from children and pets. It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor immediately for advice.

How to consume Grastim 300mcg Injection

Grastim 300mcg injection is available as a prefilled syringe. A qualified healthcare professional will administer the injection in the fatty tissues just under your skin (subcutaneously) or it will be administered as an intravenous injection into your vein slowly. The dose, route of administration, and frequency will be decided by your doctor based on your disease condition and other factors. If your physician decides that you or your caregiver can administer the Grastim 300mcg injection at home, then read the “Instructions for use” carefully from the package insert with the medicine. Your doctor or other healthcare professionals will train you on self-administration. Do not administer the medicine if you have not been trained and are not sure about the administration procedure.

Side Effects of Grastim 300mcg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
Pain in the bones, joints, and muscles
Pain at the site of Injection
Fever
Itchiness and skin rash
Nausea
Headaches
Dizziness and tiredness
Nose bleeding
Hair fall
Serious
Inflammation of Aorta
Capillary leak syndrome (plasma leaks out of tiny blood vessels)
Hypersensitivity reactions
Changes in urine color
Swelling in hands, feet, face, and abdomen
Difficulty in breathing
Sickle cell anemia

Safety Advice for Grastim 300mcg Injection

Breast Feeding
Unsafe
It is unsafe to breastfeed during the treatment with this Grastim 300mcg injection because it may cause harm to the baby. Please consult your doctor before breastfeeding.
Alcohol-unsafe
Alcohol
Unsafe
It is unsafe to consume alcohol with Grastim 300mcg injection. Please consult your doctor for more advice.
Liver-Consult your doctor
Liver
Consult Your Doctor
It is unknown whether Grastim 300mcg injection can be administered in patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with this Injection.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
It is unknown whether Grastim 300mcg injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Driving-unsafe
Driving
Unsafe
It is unsafe to travel, drive vehicles, or operate heavy machinery after taking (1 hour) Grastim 300mcg injection. Please consult your doctor.
Pregnancy-unsafe
Pregnancy
Unsafe
Grastim 300mcg injection is unsafe when administered during pregnancy because it may cause birth defects in your baby. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Word of Advice for Grastim 300mcg Injection

Inform your physician if you are experiencing any symptoms of swelling in the face, feet, hands, and abdomen, difficulty in breathing, sudden drop in blood pressure, left abdominal pain, weakness, and skin rashes. If you use the prefilled syringe, allow the medicine to warm for 30 minutes at room temperature before injecting. Read the package insert carefully if you are self-administering the medicine. This medicine may cause lung, liver, or kidney problems. Your physician may advise you to take laboratory tests regularly to monitor the effectiveness of the therapy.

FAQs about Grastim 300mcg Injection

Q1. Q1. What are the symptoms that I should notify the physician while taking Grastim 300mcg injection?

Inform your physician if you are experiencing any symptoms of swelling in the face, feet, hands, and abdomen, difficulty in breathing, sudden drop in blood pressure, left abdominal pain, weakness, and skin rashes.

Q2. Q2. What is the Grastim 300mcg injection package insert?

The FDA provides a package insert, which summarizes the relevant scientific information needed for healthcare practitioners and patients to use the drug safely and effectively. The package insert contains safety information, instruction for use, and other information.

Q3. Q3. Who should not take Grastim 300mcg injection?

Grastim 300mcg injection is not indicated for everyone. Do not take this medicine if you are allergic to any forms of rubber, latex, pegfilgrastim, filgrastim or any of the other ingredients in this medicine.

Q4. Q4. Will Grastim 300mcg injection affect my kidneys?

This medicine may affect your kidneys. Regular kidney function tests will be taken to monitor your kidney functions. Inform your physician if you have any kidney problems.

Q5. Q5. Can I breastfeed while taking Grastim 300mcg injection?

No, This medicine secretes in small amounts in breast milk. Grastim 300mcg injection can cause harm to your baby. Please consult your doctor if you are breastfeeding.

Fact Box of Grastim 300mcg Injection

Molecule Name FILGRASTIM
Marketer DR REDDY'S LABORATORIES LTD

References for Grastim 300mcg Injection

1.Neupogen Singleject 30 MU (0.6 mg/ml) - Patient Information Leaflet (PIL) - (emc) ww.medicines.org.uk. [Revised on 2022] [cited 2023 Mar 14]
2.Neupogen 30 MU (0.3 mg/ml) solution for injection - Patient Information Leaflet (PIL) - (emc). www.medicines.org.uk. [Revised on 2022] [cited 2023 Mar 14].
3.KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 876
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Grastim 300mcg Injection
₹599.00 MRP ₹1,217.81
Inclusive of all taxes 51% OFF
(You Save ₹618.81)
1 ML Injection in Prefilled Syringe

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