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Home › Medicine › Fibnib 100mg Capsule
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Fibnib 100mg Capsule

Prescription Required Cold Chain i
Salt Composition NINTEDANIB
Marketer ALKEM LABORATORIES LTD
Prepaid Only. Non-Returnable.
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This medicine is prepaid
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Introduction to Fibnib 100mg Capsule

Fibnib 100 mg Capsule contains nintedanib as its active ingredient and belongs to a class of medicines known as tyrosine kinase inhibitors. It is used in the treatment of idiopathic pulmonary fibrosis, chronic fibrosing interstitial lung disease, and interstitial lung disease associated with systemic sclerosis.

Inform your doctor if you are taking blood-thinning medicines or if you have recently undergone surgery. Effective contraception should be used during treatment and continued for at least three months after the final dose. Consult your doctor about suitable contraceptive methods, as oral birth control pills may be less effective in some women while taking this medicine.

Before starting treatment, tell your doctor if you have any existing medical conditions, particularly liver or heart problems. Your doctor may perform liver function tests regularly during the first three months of treatment. Also inform your doctor if you have a history of bleeding disorders or blood clots (arterial thromboembolic events). Fibnib 100 mg Capsule may cause liver function impairment and may harm an unborn baby.

Consult your doctor if you have any of the above conditions before using this medicine. Common side effects of Fibnib 100 mg Capsule include nausea, vomiting, diarrhoea, fever, skin ulcers, gastrointestinal perforation, abnormal liver function test results, loss of appetite, headache, weight loss, and high blood pressure. Contact your doctor immediately if you experience any side effects or if they become severe.

Uses of Fibnib 100mg Capsule

Fibnib 100mg Capsule is used in the treatment of the following:

Idiopathic pulmonary fibrosis.
Chronic fibrosing lung diseases with a progressive phenotype
Systemic sclerosis

Therapeutic Effects of Fibnib 100mg Capsule

Fibnib 100mg Capsule works by inhibiting receptor multiple tyrosine kinases (RTKs) enzymes that develop and progress lung fibrosis (scarring). Inhibiting these enzymes reduces the development of fibrous tissue in the lungs.

Interaction of Fibnib 100mg Capsule with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Fibnib 100mg Capsule and reduce effectiveness by causing undesirable side effects.

More Information about Fibnib 100mg Capsule

Before starting the treatment, it is recommended to perform a liver function test Store at the room temperature of 20°C to 25°C Protect from light and moisture Keep out of reach and sight of children and pets.

How to consume Fibnib 100mg Capsule

Take Fibnib 100mg Capsule as advised by your physician. Swallow the medicine with a glass of water. Do not crush, chew, or open the medicine. Your doctor will decide the correct dose and duration for you based on your age, body weight, and disease condition. Do not stop taking this medicine unless your doctor advises you to stop.

Side Effects of Fibnib 100mg Capsule

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious side effects of Fibnib 100mg Capsule are:
Bronchitis
Myocardial infarction
Bleeding problems
Pneumonia
Major bleeding
Yellow eyes, dark urine, pain in the upper right side of the stomach
Severe stomach cramps, bloating, fever, and chills
Chest pressure or pain on the left side of the body
Increased protein in the urine (proteinuria)
Common side effects of Fibnib 100mg Capsule are:
Nausea, vomiting, diarrhoea
Fever
Skin ulcer
Gastrointestinal perforation
Altered liver function values
Decreased appetite
Headache
Weight loss
Hypertension

Safety Advice for Fibnib 100mg Capsule

Breast Feeding
Unsafe
Taking Fibnib 100mg Capsule while breastfeeding may be unsafe because it may affect the child. Therefore, talk with your doctor to get more information.
Alcohol-Consult your doctor
Alcohol
Consult Your Doctor
It is unknown whether consuming alcohol while taking a Fibnib 100mg Capsule is safe. Please speak with your physician.
Liver-Consult your doctor
Liver
Consult Your Doctor
Inform your physician if you have liver problems because of Fibnib 100mg Capsule should be used cautiously with this condition. Before starting treatment, your physician conducts the liver function test regularly for the first three months.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
Consult your doctor if you experience symptoms like pneumonia or any other lung-related condition while taking Fibnib 100mg Capsule.
Driving-unsafe
Driving
Unsafe
While taking Fibnib 100mg Capsule, it is unsafe to drive or use machines because it may cause nausea, changes in vision, vomiting, etc. Talk to your doctor for more information.
Pregnancy-unsafe
Pregnancy
Unsafe
Fibnib 100mg Capsule is unsafe to use during pregnancy as it may cause birth defects or death to the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant, or are planning for the pregnancy before starting the treatment.

Word of Advice for Fibnib 100mg Capsule

Inform your physician if you have bleeding problems, hypertension, heart problems or weak blood vessels. Inform your physician if you experience allergic reactions to Fibnib 100mg Capsule. Notify your physician if you have recently undergone surgery, as this medicine affects the process of wound healing. Consult your physician and use an effective method of contraception while on this treatment and even after the treatment for three months. Abnormalities, such as dark or brown urine, bruises, bleeding than usual, or jaundice, must be notified immediately to your doctor. Avoid smoking while taking Fibnib 100mg Capsule because it may reduce the effectiveness of the medicine.

FAQs about Fibnib 100mg Capsule

Q1. Q1. How does a Fibnib 100mg Capsule work in the body?

Fibnib 100mg Capsule works by inhibiting several signalling pathways involved in the formation of scar tissue in the lungs. It targets the activity of certain enzymes and growth factors that promote the growth of fibroblasts, which are the cells responsible for producing collagen and other proteins that form scar tissue in the lungs.

Q2. Q2. Can Fibnib 100mg Capsule cure idiopathic pulmonary fibrosis (IPF)?

Fibnib 100mg Capsule is not a cure for idiopathic pulmonary fibrosis (IPF). It is a medication that can help slow the progression of the disease by reducing the formation of scar tissue in the lungs. It is important to continue taking this medicine as your doctor prescribes, even if you start feeling better.

Q3. Q3. How can I manage diarrhoea while taking Fibnib 100mg Capsule?

If you experience diarrhoea while taking Fibnib 100mg Capsule, staying hydrated by drinking plenty of fluids is important. Your doctor may also recommend over-the-counter medications or prescription medications to help manage your diarrhoea. If your diarrhoea is severe or persistent, you should contact your doctor.

Q4. Q4. Can Fibnib 100mg Capsule cause liver damage?

Fibnib 100mg Capsule may cause liver function abnormalities, which may indicate liver damage. It is important to have regular blood tests to monitor your liver function while taking this medicine. If you experience symptoms of liver damage, such as jaundice or abdominal pain, you should contact your doctor immediately.

Q5. Q5. What dosage of Fibnib 100mg Capsule should I take?

Your doctor will decide the correct dose and duration for you based on your age, body weight, and disease condition. Do not stop taking Fibnib 100mg Capsule unless your doctor advises you to stop. As with all medications, it is important to follow the dosage instructions provided by your healthcare provider and to consult them for any questions or concerns.

Q6. Q6. Why is the liver enzyme elevated during treatment with Fibnib 100mg Capsule?

The reason for this elevation is not completely understood, but it is thought to be related to the drug's effects on certain enzymes involved in liver function. The elevation in liver enzymes is generally mild and temporary and typically resolves on its own or with a dose adjustment of the Fibnib 100mg Capsule.

Fact Box of Fibnib 100mg Capsule

Molecule Name NINTEDANIB
Marketer ALKEM LABORATORIES LTD

References for Fibnib 100mg Capsule

1.. Boehringer Ingelheim Pharmaceuticals. Inc, [Revised on Oct 2022] [Accessed on 05th April 2023]
2.Boehringer Ingelheim, Electronics Medicines Compendium (EMC), [Revised on Aug 2021] [Accessed on 05th April 2023],
3.. Boehringer Ingelheim, U.S. Food and Drug Administration, [Revised on Mar 2020], [Accessed on 05th April 2023],
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Fibnib 100mg Capsule
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