Comtripsy 15mg Tablet

Prescription Required Cold Chain i

Salt Composition TRIFLURIDINE AND TIPIRACIL

Marketer INTAS PHARMACEUTICALS LTD

Prepaid Only. Non-Returnable.

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Introduction to Comtripsy 15mg Tablet

Comtripsy 15 mg Tablet is an anticancer medicine that contains two active ingredients: Trifluridine and Tipiracil. It is prescribed for adults with metastatic colorectal cancer (cancer of the colon or rectum that has spread to other parts of the body), particularly when other treatment options are no longer suitable or effective.

Trifluridine works by preventing cancer cells from growing and multiplying, while Tipiracil helps slow the breakdown of Trifluridine in the body, allowing it to remain effective for a longer period. Cancer is a disease in which cells grow and divide in an uncontrolled and abnormal way. This medicine is not recommended for children or adolescents under 18 years of age.

Do not take this medication if you are allergic to Trifluridine, Tipiracil, or any of its other ingredients. Before starting treatment, inform your doctor if you have kidney or liver problems or if you are lactose intolerant.

Common side effects may include:

Neutropenia (low white blood cell count)

Anemia (low red blood cell count)

Gastrointestinal issues, such as nausea or diarrhea

Contact your doctor if you notice any side effects or unusual symptoms. Patients with kidney impairment may require dose adjustments.

If you are pregnant or planning to become pregnant, inform your doctor immediately, as this medication may harm the unborn baby. Both men and women should use effective contraception during treatment and for at least six months after completing therapy.

Uses of Comtripsy 15mg Tablet

Metastatic colorectal cancer

Therapeutic Effects of Comtripsy 15mg Tablet

Trifluridine interferes with the DNA synthesis of cancer cells and inhibits the growth of cancer cells. Tipiracil stops the body from breaking down Trifluridine and increases its exposure.

Interaction of Comtripsy 15mg Tablet with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications, such as Zidovudine and others, may interact with Comtripsy 15mg Tablet and cause undesirable side effects.

More Information about Comtripsy 15mg Tablet

Keep Comtripsy 15mg Tablet out of sight and reach of children. Store at room temperature (20°C - 25°C).

How to consume Comtripsy 15mg Tablet

Take Comtripsy 15mg Tablet as advised by your physician. Usually, this medicine will be taken as a whole with a glass of water. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking this medicine if your doctor advises you to stop.

Side Effects of Comtripsy 15mg Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious

Low white blood cell count (fever, chills)

Anemia (shortness of breath, tiredness)

Diarrhea, vomiting, abdominal pain

Unusual bleeding or bruising

Severe gastrointestinal problem

Common

Lack of appetite

Nausea

Hair loss

Weight loss

Changes in taste

Constipation

Swelling in hands or feet or mucous membranes

Mouth pain

Itchy dry skin

A lower level of albumin

Increased bilirubin

Increase liver enzymes

Safety Advice for Comtripsy 15mg Tablet

Breast Feeding

Unsafe

Taking Comtripsy 15mg Tablet while breastfeeding may be unsafe because it may affect the child. Do not breastfeed for at least four months after the treatment. Therefore, talk with your doctor to get more information.

Alcohol-Consult your doctor

Alcohol

Consult Your Doctor

It is unknown whether consuming alcohol while taking a Comtripsy 15mg Tablet is safe. Please speak with your physician.

Liver-unsafe

Liver

Unsafe

Inform your physician if you have liver problems because Comtripsy 15mg Tablet should be used cautiously with this condition.

Lungs-Consult your doctor

Lungs

Consult Your Doctor

It is unknown whether Comtripsy 15mg Tablet are safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Driving-Consult your doctor

Driving

Consult Your Doctor

While taking Comtripsy 15mg Tablet, driving or using machines is unsafe because it may affect your ability to concentrate and react. Talk to your doctor for more information.

Pregnancy-unsafe

Pregnancy

Unsafe

Comtripsy 15mg Tablet are unsafe during pregnancy as they may harm the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant or planning for the pregnancy before starting the treatment. Use effective contraception.

Word of Advice for Comtripsy 15mg Tablet

Notify your doctor if you are intolerant to sugar, as this medicine contains lactose. Your doctor may adjust the dosage if you are an inpatient with a kidney condition. Comtripsy 15mg Tablet come in two strengths, usually given twice a day. Your doctor may take a blood test before each test. Discuss the effective contraception method with your doctor.

FAQs about Comtripsy 15mg Tablet

Q1. Q1. Who should not take Comtripsy 15mg Tablet?

Comtripsy 15mg Tablet should not be taken by individuals who are allergic to any of its components. It should also be avoided by individuals with severely decreased bone marrow function (reduction in blood count), severe infections, or severe renal or hepatic impairment.

Q2. Q2. Can Comtripsy 15mg Tablet be taken with other medications?

Comtripsy 15mg Tablet may interact with other medications, so it is important to inform your doctor of all the medications, vitamins, and supplements you are currently taking.

Q3. Q3. Can Comtripsy 15mg Tablet affect our immune system?

Comtripsy 15mg Tablet are not known to affect the immune system directly, but they can indirectly affect it by reducing the number of white blood cells (WBC) in the body. This can increase the risk of infections.

Q4. Q4. What should I do if I miss a dose of Comtripsy 15mg Tablet?

If you miss a dose of Comtripsy 15mg Tablet, take it as soon as you remember. Don't double dose to make up for a missed one.

Q5. Q5. At what condition is dose adjustment needed for Comtripsy 15mg Tablet?

If you are a patient with kidney disease, inform your doctor before starting the treatment because adjustment is needed in kidney-conditioned patients.

Fact Box of Comtripsy 15mg Tablet

Molecule Name	TRIFLURIDINE AND TIPIRACIL
Marketer	INTAS PHARMACEUTICALS LTD

References for Comtripsy 15mg Tablet

1. Les Laboratories Servier, Electronic medicines compendium (EMC), [Revised on Dec 2020] [Accessed on 25th April 2023],
2.Taiho Oncology, US Food, and Drug Administration, [Revised on Feb 2019] [ Accessed on 25th April 2023],
3.Celeste B Burness, Sean T Duggan; Trifluridine/Tipiracil: A Review in Metastatic Colorectal Cancer; Drugs; Published on Sep 2016; Accessed on 03/03/2022;

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Comtripsy 20mg Tablet

Comtripsy 15mg Tablet

Introduction to Comtripsy 15mg Tablet

Uses of Comtripsy 15mg Tablet

Therapeutic Effects of Comtripsy 15mg Tablet

Interaction of Comtripsy 15mg Tablet with other drugs

More Information about Comtripsy 15mg Tablet

How to consume Comtripsy 15mg Tablet

Side Effects of Comtripsy 15mg Tablet

Safety Advice for Comtripsy 15mg Tablet

Word of Advice for Comtripsy 15mg Tablet

FAQs about Comtripsy 15mg Tablet

Fact Box of Comtripsy 15mg Tablet

References for Comtripsy 15mg Tablet

Why MedXtra?

THE MEDXTRA CHECK: VERIFIED GENUINE MEDICINES AT THE BEST PRICES EVER