Azatirel 100mg Injection

Prescription Required Cold Chain i

Salt Composition AZACITIDINE

Marketer RELIANCE LIFE SCIENCES PVT LTD

Prepaid Only. Non-Returnable.

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Introduction to Azatirel 100mg Injection

Azatirel 100 mg Injection is indicated for the treatment of adults diagnosed with Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) who are not eligible for a stem cell transplant.

In Myelodysplastic Syndrome (MDS), the bone marrow does not work effectively, leading to insufficient production of normal, healthy blood cells. Acute Myeloid Leukemia (AML) is a form of bone marrow cancer characterized by the rapid production and release of immature, abnormal blood cells into the bloodstream.

Uses of Azatirel 100mg Injection

Treatment of Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Haemopoietic stem cell transplant
Intermediate-2 and High-risk Myelodysplastic syndrome (MDS)

Therapeutic Effects of Azatirel 100mg Injection

In MDS and AML, the development of tumor cells is caused by the process of transcriptional repression of various genes, which is due to the hypermethylation of DNA. Transcriptional repression is a process where proteins bind directly or indirectly to DNA and control the activity of copying a specific gene or a set of genes. The active form of Azatirel 100mg Injection binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.

Interaction of Azatirel 100mg Injection with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Azatirel100 mg injection and cause undesirable side effects.

More Information about Azatirel 100mg Injection

Store at room temperature (15-30°C). If the product is reconstituted, it must be used immediately; if not, store at 2-8°C for not more than 8 hours. Keep the injection out of sight and reach of children.

How to consume Azatirel 100mg Injection

Take Azatirel 100mg Injection only under the supervision of your physician. Your physician will decide the dose based on your height, weight, and general condition. Azatirel 100mg Injection shall be given under the skin of your thigh, stomach, or upper arm.

Side Effects of Azatirel 100mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious:

Unexpected bleeding, with blood in stool and urine

Fever

Pneumonia, is characterized by chest pain or breathlessness.

Allergic reaction with symptoms of swelling of lips, itching, or rashes.

Seizures, loss of consciousness, severe headache, or bleeding in the brain

Frequent urination with pain or burning sensation

Common:

Disturbances in the blood count (RBC, WBC, Platelets)

Nausea, vomiting, diarrhea

Constipation

Tiredness

Skin reactions like redness and pain at the site of injection

Decreased appetite

Dizziness

Pain in extremities

Joint pain

Stomach pain

Headache

Sore nose and throat

Rashes and bruising

Safety Advice for Azatirel 100mg Injection

Breast Feeding

Unsafe

Breastfeeding is not intended for patients on Azatirel 100mg Injection therapy. Consult your physician for advice.

Alcohol-Consult your doctor

Alcohol

Consult Your Doctor

It is not known whether it is safe to consume alcohol with Azatirel 100mg Injection. Please consult your doctor.

Liver-Consult your doctor

Liver

Consult Your Doctor

Inform your physician if you have been told that you have a tumor in the liver cells.

Lungs-Consult your doctor

Lungs

Consult Your Doctor

It is not known whether it is safe to administer Azatirel 100mg Injection in lung failure patients. Please consult your doctor.

Driving-unsafe

Driving

Unsafe

It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking Azatirel 100 mg injection.

Pregnancy-unsafe

Pregnancy

Unsafe

Azatirel 100mg Injection could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.

Word of Advice for Azatirel 100mg Injection

Inform the doctor if the patient has any allergy reactions, respiratory problems, kidney, liver, or heart problems, and medication taken for different medical conditions before taking this injection as they worsen the condition. Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breastfeeding mothers as this medicine causes harmful effects in the developing baby. Take this injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. It is administered under the skin of your thigh, stomach or upper arm.

FAQs about Azatirel 100mg Injection

Q1. Q1. How to use Azatirel 100mg Injection?

Take Azatirel 100mg Injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. Azatirel 100mg Injection is administered under the skin of your thigh, stomach, or upper arm.

Q2. Q2. Does Azatirel 100mg Injection cause hair loss?

No, Azatirel 100mg Injection does not cause hair loss even after using it for a prolonged period of time.

Q3. Q3. How does Azatirel 100mg Injection work?

Azatirel 100mg Injection binds to RNA and DNA, interrupts their activity in actively multiplying cells and exhibits a toxic effect on cancer cells.

Q4. Q4. Is Azatirel 100mg Injection chemotherapy?

Yes. Azatirel100mg Injection is chemotherapy, and it is used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases growth and multiplication (cytotoxic effect).

Q5. Q5. What are the side effects of Azatirel100mg Injection?

The common side effects ofAzatirel 100mg Injection are Nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of the skin, dizziness, joint pain, headache, sore throat and nose.

Q6. Q6. Is it safe to drive after taking an Azatirel100mg Injection?

It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking this medication.

Fact Box of Azatirel 100mg Injection

Molecule Name	AZACITIDINE
Marketer	RELIANCE LIFE SCIENCES PVT LTD

References for Azatirel 100mg Injection

1.K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, [May 2003], 60(4):721-741, [Accessed on 5th Apr 2021]
2.Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018 [Accessed on 3rd Apr 2021]
3.Dr.Reddy’s Laboratories, [Revised on 8th Nov 2018] [Accessed on 5th Apr 2021]

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Azatirel 100mg Injection

Introduction to Azatirel 100mg Injection

Uses of Azatirel 100mg Injection

Therapeutic Effects of Azatirel 100mg Injection

Interaction of Azatirel 100mg Injection with other drugs

More Information about Azatirel 100mg Injection

How to consume Azatirel 100mg Injection

Side Effects of Azatirel 100mg Injection

Safety Advice for Azatirel 100mg Injection

Word of Advice for Azatirel 100mg Injection

FAQs about Azatirel 100mg Injection

Fact Box of Azatirel 100mg Injection

References for Azatirel 100mg Injection

Why MedXtra?

THE MEDXTRA CHECK: VERIFIED GENUINE MEDICINES AT THE BEST PRICES EVER