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Home β€Ί Medicine β€Ί Abevmy 400mg Injection
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Abevmy 400mg Injection

Prescription Required Cold Chain i
Salt Composition BEVACIZUMAB
Marketer ERIS LIFESCIENCES LIMITED
Prepaid Only. Non-Returnable.
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This medicine is prepaid
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returned once delivered.
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Introduction to Abevmy 400mg Injection

Abevmy 400mg Injection contains the active ingredient Bevacizumab, an anticancer medication designed to inhibit tumor growth. It is prescribed in combination with other chemotherapy drugs to treat various cancers, including:

Metastatic breast cancer

Brain cancer

Cervical cancer

Kidney cancer

Lung cancer

Colorectal cancer

Ovarian, fallopian tube, and primary peritoneal cancers

Precautions and Fertility Considerations:

Use effective contraception during treatment and for at least six months after the last dose.

Abevmy is not recommended for children or adolescents under 18.

Women planning pregnancy should discuss fertility preservation, as this medication may affect ovarian function.

Breastfeeding is not recommended, as the medicine may interfere with your baby’s growth and development.

Administration and Side Effects:

Abevmy is typically given in combination with other chemotherapy drugs.

Common side effects include constipation, loss of appetite, runny nose, fever, skin reactions, and weight loss.

Before Starting Treatment:

Inform your doctor if you have high blood pressure, diabetes, stomach disorders, or heart problems.

Do not take Abevmy within 28 days before or after surgery, as it may increase the risk of poor wound healing and bleeding complications.

Notify your doctor of any dental issues requiring surgery before starting treatment.

Report immediately if you experience vision changes, confusion, or neurological symptoms, as these may indicate serious complications

Uses of Abevmy 400mg Injection

Abevmy 400mg Injection is indicated to treat the following conditions:

Glioblastoma multiforme (brain cancer)
Persistent, recurrent, or metastatic breast cancer
Metastatic cervical cancer
Advanced kidney cancer
Metastatic colorectal cancer
Advanced non-small-cell lung cancer
Liver Cancer- Hepatocellular carcinoma
Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer

Therapeutic Effects of Abevmy 400mg Injection

Abevmy 400mg Injection is a recombinant humanized monoclonal antibody that works as a targeted therapy in the treatment of various advanced cancers. It produces its action by selectively binding to the protein called vascular endothelial growth factor A (VEGF-A), present in the lining of blood and lymph vessels in the body. It interrupts the interaction of VEGF-A with its receptors. This further inhibits the formation of blood vessels that supply oxygen and nutrients to the tumor. As a result, it slows down the rate of progression of cancer.

Interaction of Abevmy 400mg Injection with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Abevmy 400mg Injection and cause undesirable side effects.

More Information about Abevmy 400mg Injection

Store Abevmy 400mg Injection at 2˚C to 8˚C. Do not freeze or shake. Protect from light. Keep out of reach of children.

How to consume Abevmy 400mg Injection

Your physician or nurse will administer Abevmy 400mg Injection as an intravenous infusion. The infusion should be given immediately after the dilution.

Side Effects of Abevmy 400mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious:
Headache
Vision changes
Confusion
Severe allergic reactions
High Blood pressure
Delayed wound healing following surgery
Protein in urine
Severe infections
Blood clots in arteries and blood vessels of lungs
Gut perforation
Nosebleeds and bleeding risk
Heart problems with an increase in heart rate
Mouth sores, dryness
Shortness of breath
Common:
Numbness in hands or feet
Weakness and lack of energy
Diarrhoea, nausea, vomiting, abdominal pain
Constipation
Loss of appetite
Weight loss
Changes in taste and speech
Decrease in counts of white blood cells
Fever
Dry skin
Back pain

Safety Advice for Abevmy 400mg Injection

Breast Feeding
Unsafe
It is recommended to avoid breastfeeding for a minimum of 6 months after your treatment with Abevmy 400mg Injection as this medicine may interfere with the growth of your child.
Alcohol-Consult your doctor
Alcohol
Consult Your Doctor
Consult your doctor to know if it is safe to consume alcohol while you are on treatment with Abevmy 400mg Injection as only limited studies are available.
Liver-Consult your doctor
Liver
Consult Your Doctor
Inform your physician before starting Abevmy 400mg Injection if you have liver diseases to avoid any serious side effects.
Lungs-Consult your doctor
Lungs
Consult Your Doctor
Inform your doctor if you have any lung conditions before starting treatment with Abevmy 400mg injection
Driving-unsafe
Driving
Unsafe
Avoid driving or using machinery while you are on your treatment with Abevmy 400mg Injection as it is related to cause dizziness or sleepiness.
Pregnancy-unsafe
Pregnancy
Unsafe
Inform your physician before starting your treatment with Abevmy 400mg Injection in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Word of Advice for Abevmy 400mg Injection

It is vital to inform your physician before taking Abevmy 400mg Injection if you have the following conditions: Have conditions involving inflammation in the stomach (ulcer, colitis). Experience allergic reactions to Abevmy 400mg Injection or its ingredients. Have recently undergone surgery as it is associated with the risk of bleeding. Have diabetes, hypertension, or heart problems.

FAQs about Abevmy 400mg Injection

Q1. Q1. Is Abevmy 400mg Injection used as standalone treatment in cancers?

Abevmy 400mg Injection is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

Q2. Q2. Is it safe for women to use Abevmy 400mg Injection?

While for women with reproductive potential subjected to Abevmy 400mg Injection, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.

Q3. Q3. Is it safe to undergo a surgery during the treatment with Abevmy 400mg Injection?

Abevmy 400mg Injection is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

Q4. Q4. Do the side effects of Abevmy 400mg Injection last for a chronic period?

All the side effects that are relatively caused by Abevmy 400mg Injection occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

Q5. Q5. What is the method of administration for Abevmy 400mg Injection?

Abevmy 400mg Injection is administered through intravenous infusion. The dosage is calculated based on the patient’s body weight, height, and age. The first infusion typically takes 90 minutes, and if well tolerated, the duration may be reduced to 30 minutes for future doses.

Q6. Q6. Can I take Abevmy 400mg Injection if I am pregnant?

Inform your physician before starting your treatment with Abevmy 400mg Injection in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Fact Box of Abevmy 400mg Injection

Molecule Name BEVACIZUMAB
Marketer ERIS LIFESCIENCES LIMITED

References for Abevmy 400mg Injection

1. Roche Products Limited, Electronic Medicines Compendium (EMC), [Revised on Jan 2022] [Accessed on 21/11/2022],
2. G.G. Dark, A.R. Abdul Razak, Oncology, Davidson's Principles & Practice of Medicine, 22nd Edition, 2014, 259-282.
3. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
4. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
5. Roche Group, U.S FDA, [Revised on Jan 2021][ Accessed on 21/11/2022],6. Roche Group,Bevacizumab Injection, Indication,[Revised on 2020] [Accessed on 21/11/2022
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Abevmy 400mg Injection
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16 ML Injection in Vial

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